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Michael Maes Selected Research

Aryldialkylphosphatase (Paraoxonase)

5/2022Deficit schizophrenia and its features are associated with PON1 Q192R genotypes and lowered paraoxonase 1 (PON1) enzymatic activity: effects on bacterial translocation - CORRIGENDUM.
2/2022Correction to: Increased Levels of Plasma Tumor Necrosis Factor-α Mediate Schizophrenia Symptom Dimensions and Neurocognitive Impairments and Are Inversely Associated with Natural IgM Directed to Malondialdehyde and Paraoxonase 1 Activity.
1/2021Deficit schizophrenia and its features are associated with PON1 Q192R genotypes and lowered paraoxonase 1 (PON1) enzymatic activity: effects on bacterial translocation.
1/2021Towards a new model and classification of mood disorders based on risk resilience, neuro-affective toxicity, staging, and phenome features using the nomothetic network psychiatry approach.
1/2021Menstruation distress is strongly associated with hormone-immune-metabolic biomarkers.
11/2020Lowered Antioxidant Defenses and Increased Oxidative Toxicity Are Hallmarks of Deficit Schizophrenia: a Nomothetic Network Psychiatry Approach.
5/2020Increased Levels of Plasma Tumor Necrosis Factor-α Mediate Schizophrenia Symptom Dimensions and Neurocognitive Impairments and Are Inversely Associated with Natural IgM Directed to Malondialdehyde and Paraoxonase 1 Activity.
11/2019Schizophrenia phenomenology comprises a bifactorial general severity and a single-group factor, which are differently associated with neurotoxic immune and immune-regulatory pathways.
1/2019Why Should Psychiatrists and Neuroscientists Worry about Paraoxonase 1?
10/2018Generalized Anxiety Disorder (GAD) and Comorbid Major Depression with GAD Are Characterized by Enhanced Nitro-oxidative Stress, Increased Lipid Peroxidation, and Lowered Lipid-Associated Antioxidant Defenses.
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Michael Maes Research Topics

Disease

71Schizophrenia (Dementia Praecox)
09/2022 - 04/2002
66Inflammation (Inflammations)
06/2022 - 09/2002
42Chronic Fatigue Syndrome (Myalgic Encephalomyelitis)
04/2022 - 10/2005
34Fatigue
04/2022 - 10/2006
31Mood Disorders (Mood Disorder)
08/2022 - 11/2003
31Bipolar Disorder (Manic Depressive Psychosis)
06/2022 - 09/2002
29Psychotic Disorders (Schizoaffective Disorder)
10/2022 - 01/2004
29Major Depressive Disorder (Major Depressive Disorders)
08/2022 - 01/2014
25Depressive Disorder (Melancholia)
04/2021 - 02/2005
20Infections
01/2022 - 10/2003
15Mental Disorders (Mental Disorder)
08/2022 - 12/2002
15Cognitive Dysfunction
01/2022 - 02/2012
15Mitochondrial Diseases (Mitochondrial Disease)
01/2021 - 12/2012
14Medically Unexplained Symptoms
04/2022 - 02/2012
14Multiple Sclerosis
05/2020 - 01/2011
13Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2020 - 01/2011
12Alzheimer Disease (Alzheimer's Disease)
01/2022 - 01/2014
11Pain (Aches)
01/2022 - 10/2006
11Neuroinflammatory Diseases
01/2022 - 11/2012
10Neoplasms (Cancer)
01/2022 - 02/2002
10Insulin Resistance
01/2022 - 11/2014
10Autistic Disorder (Autism)
01/2021 - 01/2002
10Parkinson Disease (Parkinson's Disease)
01/2021 - 12/2013
9COVID-19
07/2022 - 05/2020
9Fibromyalgia (Fibrositis)
01/2022 - 12/2013
9Tobacco Use Disorder (Nicotine Dependence)
11/2021 - 06/2014
8Necrosis
01/2021 - 12/2002
7Autism Spectrum Disorder
01/2022 - 01/2018
7Anxiety Disorders (Anxiety Disorder)
11/2021 - 12/2012
7Obesity
12/2020 - 01/2011
6Treatment-Resistant Depressive Disorder
04/2022 - 02/2004
6Wounds and Injuries (Trauma)
01/2022 - 08/2010
6Dysbiosis
02/2020 - 01/2017
6Premenstrual Syndrome (Premenstrual Tension)
01/2020 - 12/2016
6Postpartum Depression (Post-Natal Depression)
02/2018 - 12/2007
6Disease Progression
12/2017 - 03/2016
5Iron Overload
06/2022 - 01/2018
5Stroke (Strokes)
02/2022 - 01/2011
5Mania (Manias)
01/2021 - 06/2002

Drug/Important Bio-Agent (IBA)

69Biomarkers (Surrogate Marker)IBA
06/2022 - 01/2012
57CytokinesIBA
06/2022 - 01/2002
54Tryptophan (L-Tryptophan)FDA Link
09/2022 - 09/2002
37Immunoglobulin M (IgM)IBA
02/2022 - 10/2003
32AntioxidantsIBA
01/2022 - 10/2006
29Immunoglobulin A (IgA)IBA
07/2021 - 04/2007
28Proteins (Proteins, Gene)FDA Link
08/2022 - 06/2002
24Pharmaceutical PreparationsIBA
03/2022 - 01/2004
24Antidepressive Agents (Antidepressants)IBA
04/2021 - 12/2002
20Biological ProductsIBA
01/2021 - 01/2004
19Interleukin-6 (Interleukin 6)IBA
03/2022 - 12/2002
19Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2022 - 12/2002
17Interleukin-10 (Interleukin 10)IBA
03/2022 - 12/2002
16Aryldialkylphosphatase (Paraoxonase)IBA
05/2022 - 04/2014
16Malondialdehyde (Propanedial)IBA
02/2022 - 04/2011
15ZincIBA
12/2022 - 12/2005
15InterleukinsIBA
03/2022 - 02/2005
15Serotonin (5 Hydroxytryptamine)IBA
01/2022 - 03/2005
14LipidsIBA
03/2021 - 10/2006
12C-Reactive ProteinIBA
03/2022 - 04/2011
10KynurenineIBA
09/2022 - 09/2002
10Toll-Like Receptors (Toll-Like Receptor)IBA
01/2022 - 04/2011
10Advanced Oxidation Protein Products (AOPP)IBA
11/2021 - 11/2017
10Nitric Oxide (Nitrogen Monoxide)FDA Link
08/2020 - 02/2012
10AntibodiesIBA
10/2019 - 03/2003
9CalciumIBA
12/2022 - 03/2017
9EnzymesIBA
09/2022 - 12/2007
9Polytetrafluoroethylene (Teflon)FDA Link
10/2021 - 10/2014
9HaptoglobinsIBA
01/2021 - 03/2005
9HDL CholesterolIBA
01/2021 - 04/2014
9Glutathione (Reduced Glutathione)IBA
01/2021 - 04/2011
9Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
09/2020 - 12/2005
8Opioid Analgesics (Opioids)IBA
12/2022 - 01/2019
8InterferonsIBA
01/2022 - 02/2005
8Antipsychotic Agents (Antipsychotics)IBA
10/2021 - 04/2002
8Uric Acid (Urate)IBA
10/2020 - 07/2015
8EpitopesIBA
02/2020 - 02/2012
8Fatty Acids (Saturated Fatty Acids)IBA
01/2020 - 05/2004
8DNA (Deoxyribonucleic Acid)IBA
04/2019 - 01/2009
8NeopterinIBA
12/2012 - 07/2003
7MagnesiumIBA
12/2022 - 12/2012
7AlbuminsIBA
04/2022 - 10/2016
7ChemokinesIBA
03/2021 - 05/2018
7HDL LipoproteinsIBA
01/2021 - 04/2014
7MelatoninIBA
03/2017 - 06/2012
6Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
09/2022 - 04/2011
6Brain-Derived Neurotrophic Factor (BDNF)IBA
08/2022 - 04/2011
6Neurotransmitter Agents (Neurotransmitter)IBA
01/2022 - 02/2005
6Messenger RNA (mRNA)IBA
01/2022 - 05/2012
6Glucose (Dextrose)FDA LinkGeneric
12/2021 - 11/2014
6IronIBA
05/2021 - 01/2017
6Interleukin-17 (Interleukin 17)IBA
04/2021 - 10/2015
6oxidized low density lipoproteinIBA
01/2021 - 09/2010
6Interleukin-4 (Interleukin 4)IBA
05/2020 - 11/2014
6Hydrocortisone (Cortisol)FDA LinkGeneric
01/2020 - 10/2004
6coenzyme Q10 (CoQ10)IBA
12/2013 - 01/2009
5CopperIBA
12/2022 - 03/2021
5EndorphinsIBA
12/2022 - 11/2019
5CateninsIBA
04/2022 - 08/2019
5CholesterolIBA
01/2021 - 05/2004

Therapy/Procedure

11Therapeutics
04/2022 - 01/2004